CURRICULUM VITAE

NAME 

Lynn E. Dobrunz

CITIZENSHIP 

United States

BUSINESS ADDRESS 

Department of Neurobiology, CIRC 590
1530 3rd Ave South,
University of Alabama at Birmingham
Birmingham, AL 35294-0021
Phone: (205) 934-7923
FAX: (205) 934-6571
E-mail: dobrunz@nrc.uab.edu

BIRTHDATE / PLACE 

April 17, 1966, Peoria, IL

EDUCATION

1988 Harvard University, S.B., Engineering Science/Bioengineering

1994 The Johns Hopkins University School of Medicine, Ph.D., Biomedical Engineering

POSITIONS HELD

1999-present Assistant Professor (Primary), Department of Neurobiology, University of Alabama at Birmingham, Birmingham, AL

2002-present Assistant Professor (Secondary), Department of Physiology and Biophysics, University of Alabama at Birmingham, Birmingham, AL

2002-present Assistant Professor (Secondary), Department of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, AL

1994-1999 Postdoctoral Fellow with Dr. Charles F. Stevens, Howard Hughes Medical Institute, The Salk Institute for Biological Studies, Department of Molecular Neurobiology, La Jolla, CA

AWARDS AND HONORS

1999-2000 Howard Hughes Medical Institute Career Development Award, UAB

1988-1991 National Science Foundation Award for Creativity in Engineering

1988-1989 Able Wolman Fellowship, The Johns Hopkins University

Magna Cum Laude, Harvard University

Phi Beta Kappa

1987-1988 John Harvard Scholarship, Harvard University

1986-1987 Harvard College Scholarship

1987 Ford Foundation Summer Research Award

1984 Elizabeth Carey Agassiz Award, Harvard University

PROFESSIONAL AFFILIATIONS

Society for Neuroscience

Women in Neuroscience

PUBLICATIONS

Manuscripts and Chapters

Dobrunz, L.E. and C.C. Garner. (2002) Priming Plasticity. Nature 415:277-278. Link to publication PDF.

Dobrunz, L.E. (2002) Release Probability is Regulated by the Size of the Readily Releasable Vesicle Pool at Excitatory Synapses in Hippocampus. Intl. J. Dev. Neurosci., 20:225-236. Link to publication PDF.

Dobrunz, L.E. and C.F. Stevens. (1999) Response of hippocampal synapses to natural stimulus patterns. Neuron 22:157-166. Link to publication PDF.

Dobrunz, L.E. (1998) Long-term potentiation and the computational synapse. Proc. Natl. Acad. Sci USA 95:4086-4088. Link to publication PDF.

Dobrunz, L.E. and C.F. Stevens. (1997) Heterogeneity of release probability, facilitation, and depletion at central synapses. Neuron 18:995-1008. Link to publication PDF.

Dobrunz, L.E., E.P. Huang, and C.F. Stevens. (1997) Very short-term plasticity in hippocampal synapses. Proc. Natl. Acad. Sci. USA. 94:14843-14847. Link to publication PDF.

Zador, A.M. and L.E. Dobrunz. (1997) Dynamic synapses in the cortex. Neuron 19:1-4. Link to publication PDF.

Dobrunz, L.E., P.H. Backx, and D.T. Yue. (1995) Steady-state [Ca^2+]i-force relationship in intact twitching cardiac muscle: direct evidence for modulation by isoproterenol and EMD 53998. Biophys. J. 69: 189-201.

Dobrunz, L.E. and M.R. Berman. (1994) Effect of temperature on Ca2+- dependent and mechanical modulators of relaxation. J. Mol. Cell Cardiol. 26:243-250.

Dobrunz, L.E., D.G. Pelletier, and T.A. McMahon. (1992) Muscle stiffness measured under conditions simulating natural sound production. Biophys. J. 51:775-783.

Frangioni, J.V., T.S. Kwan-Gett, L.E. Dobrunz, T.A. McMahon. (1987) The mechanism of low frequency sound production in muscle. Biophys. J. 51:775-783.

Manuscripts Submitted Or In Preparation

Scheiderer, C.L., K. Kolasa, M. Ward, D. Parsons, L.E. Harrell, L.E. Dobrunz, and L.L. McMahon. 2003. Sympathetic sprouting rescues plasticity at a central synapse, in preparation.

Ranels, H.J., N.C. Mills, T.C. Chang, J. de Kay, and L.E. Dobrunz. 2003. Developmental Changes in Short-term Plasticity Alter the Signal Transfer Characteristics of Hippocampal Synapses, in preparation.

Sun, H.Y, S.A. Lyons, and L.E. Dobrunz. 2003. Short-term plasticity is different at Schaffer collateral excitatory synapses onto interneurons vs. pyramidal cells in rat hippocampus, in preparation.

Published Abstracts

Scheiderer, C.L., L.E. Dobrunz, and L.L. McMahon. 2003. Interactions between NE LTD and mLTD at excitatory CA3-CA1 synapses in rat hippocampal slices, Soc Neurosci Abstr. 255.8.

Speed, H. and L.E. Dobrunz. 2004. Developmental changes in the role of metabotropic glutamate receptors in hippocampal short-term plasticity. Soc Neurosci Abstr, in press.

Sun, H.Y. and L.E. Dobrunz. 2004. Model predicts differences in short-term plasticity of excitatory hippocampal synapses in response to Natural Stimulus Pattern. Soc Neurosci Abstr, in press.

Sun, H.Y, S.A. Lyons, and L.E. Dobrunz. 2003. Short-term plasticity is different at Schaffer collateral excitatory synapses onto interneurons vs. pyramidal cells in rat hippocampus, Soc Neurosci Abstr. 808.2. 

Dobrunz, L.E., S.A. Lyons, and H.Y. Sun. 2003. Excitatory synapses onto somatostatin-containing interneurons in hippocampus have very large short-term facilitation, Soc Neurosci Abstr. 808.1.

Lyons, S.A., C.C. Garner, and L.E. Dobrunz. 2003. Formation and function of nascent synapses in hippocampal cocultures. Soc Neurosci Abstr.

Jovov, B, S.A. Lyons, L.E. Dobrunz, L.L. McMahon, and D.J. Benos. 2003. Synaptic localization of the acid sensing ion channels 1a and 2a in rat hippocampal neurons. FASEB J., 17:A78.2.

Dobrunz, L.E. 2002. Release probability per vesicle is heterogeneous at excitatory CA3-CA1 synapses in hippocampus. Soc Neurosci Abstr 28:548.2.

Scheiderer, C.L., K. Kolasa, D. Parsons, L.E. Harrell, L.E. Dobrunz, and L.L. McMahon. 2002. Activation of alpha1 adrenergic receptors induces long-term depression at excitatory CA3-CA1 synapses in rat hippocampus. Soc Neurosci Abstr 28:648.12

Scheiderer, C.L., L.E. Dobrunz, and L.L. McMahon. 2001. Activation of muscarinic M1 receptors induces LTD in the CA1 region of rat hippocampus. Soc Neurosci Abstr 27:388.14

Dobrunz, L.E. 2000. Changes in signal transfer characteristics of synapses during neonatal development. Soc Neurosci Abstr 26:519.4.

Dobrunz, L.E. and C.F. Stevens. 1998. Response of hippocampal synapses to natural stimulus patterns. Soc Neurosci Abstr 24:204.8.

Dobrunz, L.E. and C.F. Stevens. 1997 Release probability related to size of readily-releasable vesicle pool in central synapses. Soc Neurosci Abstr 23:467.18.

Dobrunz, L.E. and C.F. Stevens. 1996. History of synaptic use determines strength of central synapses. Prog. Biophys. Mol. Biol. (65) 1:187.

Dobrunz, L.E., P.H. Backx, and D.T. Yue. 1994. Sensitization agent EMD 53998 causes leftward shift of steady-state tension [Ca2+]i relationship intact twitching cardiac muscle. Biophys. J. 66:318a

Dobrunz, L.E., P.H. Backx, and D.T. Yue. 1993. Steady-state calcium-force relationship in intact cardiac muscle: evidence for desensitization by Isoproterenol. Biophys. J. 64:199a.

Berman, M.R. and L.E. Dobrunz. 1993. Phenylephrine does not alter relaxation kinetics in rat myocardium. Biophys. J. 64:255a.

L.E. Dobrunz and Berman, M.R. 1992. Effect of temperature on load dependence of relaxation. Biophys. J. 61:19a.

Berman, M.R. and L.E. Dobrunz. 1991. Load dependence of relaxation is attenuated by Nifedipine. Biophys. J. 59:420a.

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